How does POI affect fertility?

• A. It has no effect on fertility
• B. POI leads to reduced fertility and increased risk of infertility
• C. POI increases fertility
• D. POI guarantees infertility

Answer: (B)

Premature ovarian insufficiency reduces the number and quality of eggs, leading to a diminished ovarian reserve. With fewer viable eggs and often irregular or absent ovulation, the chances of conceiving naturally are decreased and the overall risk of infertility is higher than in typical reproductive aging. Some people with POI can become pregnant, either spontaneously or with fertility treatments such as assisted reproduction using donor eggs or IVF, but fertility is not restored to normal levels. In short, POI lowers fertility and increases the likelihood of infertility.