Polycystic ovary syndrome is best described as which combination?

• A. Hyperandrogenism, ovulatory dysfunction, and polycystic ovaries
• B. Endometriosis with fibroids
• C. Autoimmune thyroid disease
• D. Primary ovarian insufficiency

Answer: (A)

Polycystic ovary syndrome is defined by a trio of features centered on excess androgens, disrupted ovulation, and ovaries that have a polycystic appearance. The best description is the combination of hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. Clinically, hyperandrogenism shows up as hirsutism, acne, or alopecia; ovulatory dysfunction means irregular, infrequent, or absent ovulation with corresponding menstrual irregularities; and the ultrasound finding is ovaries with many small follicles. Together, these elements capture the characteristic profile of PCOS. The other choices point to different conditions (endometriosis with fibroids, autoimmune thyroid disease, or primary ovarian insufficiency) and do not describe the PCOS triad.