What is the role of vaginal moisturizers and lubricants in managing genitourinary syndrome of menopause (GSM)?

• A. They are the sole treatment necessary for GSM.
• B. They are first-line for mild GSM and safe for long-term use.
• C. They should be avoided due to safety concerns.
• D. They cure GSM in all cases.

Answer: (B)

Non-hormonal vaginal moisturizers and lubricants provide symptom relief by addressing the dryness and friction that come with genitourinary syndrome of menopause. For mild GSM, they are considered first-line because they are safe for long-term use and can be used regularly to improve vaginal hydration and comfort without introducing hormones. They help with daily comfort and during intercourse, but they do not reverse the underlying tissue changes of GSM, nor do they cure the condition. In cases with more pronounced atrophy or urinary symptoms, vaginal estrogen or other therapies may be needed in addition to or instead of moisturizers and lubricants. If irritation occurs, trying a different product or formulation can help, but these products are generally safe and appropriate for long-term use in many patients.