Which hormonal change is associated with the menopause transition?

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Multiple Choice

Which hormonal change is associated with the menopause transition?

Explanation:
The menopause transition is driven by shrinking ovarian reserve, which reduces estrogen and inhibin B production. That loss of negative feedback on the pituitary pushes gonadotropin release upward, with FSH rising more prominently and consistently than LH. This makes an increase in FSH the most characteristic hormonal change of the transition. Estrogen definitely falls, and LH can rise as well, but the standout change you’re looking for is rising FSH. Elevated testosterone isn’t a hallmark feature, and decreased LH is not what typically occurs.

The menopause transition is driven by shrinking ovarian reserve, which reduces estrogen and inhibin B production. That loss of negative feedback on the pituitary pushes gonadotropin release upward, with FSH rising more prominently and consistently than LH. This makes an increase in FSH the most characteristic hormonal change of the transition. Estrogen definitely falls, and LH can rise as well, but the standout change you’re looking for is rising FSH. Elevated testosterone isn’t a hallmark feature, and decreased LH is not what typically occurs.

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